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1

Interactions between dyslipidemia and the immune system and their relevance as putative therapeutic targets in atherosclerosis

Lacy, Michael, Atzler, Dorothee, Liu, Rongqi, de Winther, Menno, Weber, Christian, Lutgens, Esther

Journal:

Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 3.55 MB

english, 2018

2

Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice

Tuñón, José, Bäck, Magnus, Badimón, Lina, Bochaton-Piallat, Marie-Luce, Cariou, Bertrand, Daemen, Mat J, Egido, Jesus, Evans, Paul C, Francis, Sheila E, Ketelhuth, Daniel FJ, Lutgens, Esther, Matter,

Journal:

European Journal of Preventive Cardiology

Year:

2018

Language:

english

File:

PDF, 348 KB

english, 2018

3

Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology

Tuñón, José, Badimón, Lina, Bochaton-Piallat, Marie-Luce, Cariou, Bertrand, Daemen, Mat J, Egido, Jesus, Evans, Paul C, Hoefer, Imo E, Ketelhuth, Daniel F J, Lutgens, Esther, Matter, Christian M, Mona

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 527 KB

english, 2018

4

Liposome-enhanced MRI of neointimal lesions in the ApoE-KO mouse

Willem J.M. Mulder, Kim Douma, Gerben A. Koning, Marc A. van Zandvoort, Esther Lutgens, Mat J. Daemen, Klaas Nicolay, Gustav J. Strijkers

Journal:

Magnetic Resonance in Medicine

Year:

2006

Language:

english

File:

PDF, 353 KB

english, 2006

5

The dynamic extracellular matrix: intervention strategies during heart failure and atherosclerosis

Sylvia Heeneman, Jack P Cleutjens, Birgit C Faber, Esther E Creemers, Robert-Jan van Suylen, Esther Lutgens, Kitty B Cleutjens, Mat J Daemen

Journal:

The Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 139 KB

english, 2003

6

Requirement for CD154 in the progression of atherosclerosis

Lutgens, Esther, Gorelik, Leonid, Daemen, Mat J.A.P., de Muinck, Ebo D., Grewal, Iqbal S., Koteliansky, Victor E., Flavell, Richard A.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 353 KB

english, 1999

7

CD40 and Its Ligand in Atherosclerosis

Esther Lutgens, Dirk Lievens, Linda Beckers, Marjo Donners, Mat Daemen

Journal:

Trends in Cardiovascular Medicine

Year:

2007

Language:

english

File:

PDF, 481 KB

english, 2007

8

Paraoxonase 1 (PON-1) is expressed in the murine vessel wall and is downregulated during the progression of atherosclerosis

Mirjam Meijer, Esther Lutgens, Mat Daemen, Ann-Pascale Bijnens

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 49 KB

english, 2006

9

Deficient CD40–TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response towards an anti-inflammatory profile

Journal:

Vascular Pharmacology

Year:

2012

Language:

english

File:

PDF, 55 KB

english, 2012

10

CD40-CD40L Interactions in Atherosclerosis

Esther Lutgens, Mat J.A.P Daemen

Journal:

Trends in Cardiovascular Medicine

Year:

2002

Language:

english

File:

PDF, 817 KB

english, 2002

11

The immunobiology of CD154–CD40–TRAF interactions in atherosclerosis

David Engel, Tom Seijkens, Marjorie Poggi, Maryam Sanati, Larissa Thevissen, Linda Beckers, Erwin Wijnands, Dirk Lievens, Esther Lutgens

Journal:

Seminars in Immunology

Year:

2009

Language:

english

File:

PDF, 276 KB

english, 2009

12

Chronic Exposure to the Carcinogenic Compound Benzo[a]Pyrene Induces Larger and Phenotypically Different Atherosclerotic Plaques in ApoE-Knockout Mice

Daniëlle M.J. Curfs, Esther Lutgens, Marion J.J. Gijbels, Mark M. Kockx, Mat J.A.P. Daemen, Frederik J. van Schooten

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 528 KB

english, 2004

13

Cathepsin K gene disruption does not affect murine aneurysm formation

Lili Bai, Linda Beckers, Erwin Wijnands, Suzanne P.M. Lutgens, M. Verónica Herías, Paul Saftig, Mat J.A.P. Daemen, Kitty Cleutjens, Esther Lutgens, Erik A.L. Biessen, Sylvia Heeneman

Journal:

Atherosclerosis

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

14

HMG-coA reductase inhibitors: lipid-lowering and beyond

Esther Lutgens, Mat J.A.P. Daemen

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2004

Language:

english

File:

PDF, 123 KB

english, 2004

15

CD40 Ligand+ Microparticles From Human Atherosclerotic Plaques Stimulate Endothelial Proliferation and Angiogenesis: A Potential Mechanism for Intraplaque Neovascularization

Aurélie S. Leroyer, Pierre-Emmanuel Rautou, Jean-Sébastien Silvestre, Yves Castier, Guy Lesèche, Cécile Devue, Micheline Duriez, Ralf P. Brandes, Esther Lutgens, Alain Tedgui, Chantal M. Boulanger

Journal:

Journal of the American College of Cardiology

Year:

2008

Language:

english

File:

PDF, 693 KB

english, 2008

16

Distribution of macrophage polarization markers in human atherosclerosis

Stöger, J. Lauran, Gijbels, Marion J.J., van der Velden, Saskia, Manca, Marco, van der Loos, Chris M., Biessen, Erik A.L., Daemen, Mat J.A.P., Lutgens, Esther, de Winther, Menno P.J.

Journal:

Atherosclerosis

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

17

High Expression of C5L2 Correlates with High Proinflammatory Cytokine Expression in Advanced Human Atherosclerotic Plaques

Vijayan, Santosh, Asare, Yaw, Grommes, Jochen, Soehnlein, Oliver, Lutgens, Esther, Shagdarsuren, Gansuvd, Togtokh, Ariunaa, Jacobs, Michael J., Fischer, Jens W., Bernhagen, Jürgen, Weber, Christian, S

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

18

Sensitivity of low energy brachytherapy Monte Carlo dose calculations to uncertainties in human tissue composition

Landry, Guillaume, Reniers, Brigitte, Murrer, Lars, Lutgens, Ludy, Bloemen-Van Gurp, Esther, Pignol, Jean-Philippe, Keller, Brian, Beaulieu, Luc, Verhaegen, Frank

Journal:

Medical Physics

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

19

Regulation of atherosclerotic plaque inflammation

Bäck, Magnus, Weber, Christian, Lutgens, Esther

Journal:

Journal of Internal Medicine

Year:

2015

Language:

english

File:

PDF, 440 KB

english, 2015

20

Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis

Smeets, Esther, Meiler, Svenja, Lutgens, Esther

Journal:

Current Opinion in Lipidology

Year:

2013

Language:

english

File:

PDF, 251 KB

english, 2013

21

Atherosclerosis

Winkels, Holger, Weber, Christian, Lutgens, Esther, Gerdes, Norbert

Journal:

Current Opinion in Lipidology

Year:

2014

Language:

english

File:

PDF, 133 KB

english, 2014

22

Targeting the adaptive immune system: new strategies in the treatment of atherosclerosis

Zarzycka, Barbara, Nicolaes, Gerry A F, Lutgens, Esther

Journal:

Expert Review of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

23

INFLAMMATION, BUT NOT RECRUITMENT, OF ADIPOSE TISSUE MACROPHAGES REQUIRES SIGNALING THROUGH MAC-1 IN DIET-INDUCED OBESITY (DIO)

Wolf, Dennis, Michel, Nathaly Anto, Nora, Bukosza, Engel, David, Poggi, Marjorie, Weber, Christian, Bode, Christoph, Peter, Karlheinz, Lutgens, Esther, Zirlik, Andreas

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 246 KB

english, 2015

24

Critical assessment of intramodality 3D ultrasound imaging for prostate IGRT compared to fiducial markers

van der Meer, Skadi, Bloemen-van Gurp, Esther, Hermans, Jolanda, Voncken, Robert, Heuvelmans, Denys, Gubbels, Carol, Fontanarosa, Davide, Visser, Peter, Lutgens, Ludy, van Gils, Francis, Verhaegen, Fr

Journal:

Medical Physics

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

25

Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction

Yamano, Tomoyoshi, Nedjic, Jelena, Hinterberger, Maria, Steinert, Madlen, Koser, Sandra, Pinto, Sheena, Gerdes, Norbert, Lutgens, Esther, Ishimaru, Naozumi, Busslinger, Meinrad, Brors, Benedikt, Kyews

Journal:

Year:

2015

Language:

english

File:

PDF, 2.53 MB

english, 2015

26

Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms

Boshuizen, Marieke C.S., Hoeksema, Marten A., Neele, Annette E., van der Velden, Saskia, Hamers, Anouk A.J., Van den Bossche, Jan, Lutgens, Esther, de Winther, Menno P.J.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

27

Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential

Spitz, Charlotte, Winkels, Holger, Bürger, Christina, Weber, Christian, Lutgens, Esther, Hansson, Göran K., Gerdes, Norbert

Journal:

Cellular and Molecular Life Sciences

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

28

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis

van der Valk, Fleur M., Schulte, Dominik M., Meiler, Svenja, Tang, Jun, Zheng, Kang He, Van den Bossche, Jan, Seijkens, Tom, Laudes, Matthias, de Winther, Menno, Lutgens, Esther, Alaarg, Amr, Metselaa

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

29

CD40 in coronary artery disease: a matter of macrophages?

Jansen, Matthijs F., Hollander, Maurits R., van Royen, Niels, Horrevoets, Anton J., Lutgens, Esther

Journal:

Basic Research in Cardiology

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

30

Resveratrol Inhibits Aortic Root Dilatation in the Fbn1 C1039G/+ Marfan Mouse Model

Hibender, Stijntje, Franken, Romy, van Roomen, Cindy, ter Braake, Anique, van der Made, Ingeborg, Schermer, Edith E., Gunst, Quinn, van den Hoff, Maurice J., Lutgens, Esther, Pinto, Yigal M., Groenink

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2016

Language:

english

File:

PDF, 1.91 MB

english, 2016

31

Atherosclerosis

Meiler, Svenja, Lutgens, Esther, Weber, Christian, Gerdes, Norbert

Journal:

Current Opinion in Lipidology

Year:

2016

Language:

english

File:

PDF, 131 KB

english, 2016

32

Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis

Tjwa, Marc, Moons, Lieve, Lutgens, Esther

Journal:

Current Opinion in Lipidology

Year:

2009

Language:

english

File:

PDF, 508 KB

english, 2009

33

Atherosclerosis

Schaftenaar, Frank, Frodermann, Vanessa, Kuiper, Johan, Lutgens, Esther

Journal:

Current Opinion in Lipidology

Year:

2016

Language:

english

File:

PDF, 245 KB

english, 2016

34

Atherosclerosis

Bürger, Christina, Weber, Christian, Lutgens, Esther, Gerdes, Norbert

Journal:

Current Opinion in Lipidology

Year:

2015

Language:

english

File:

PDF, 134 KB

english, 2015

35

Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4 + T-Cell Responses

Meiler, Svenja, Smeets, Esther, Winkels, Holger, Shami, Annelie, Pascutti, Fernanda M., Nolte, Martijn A., Beckers, Linda, Weber, Christian, Gerdes, Norbert, Lutgens, Esther

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2016

Language:

english

File:

PDF, 1.60 MB

english, 2016

36

Alterations in systemic levels of Th1, Th2, and Th17 cytokines in overweight adolescents and obese mice

Jung, Christian, Lichtenauer, Michael, Strodthoff, Daniela, Winkels, Holger, Wernly, Bernhard, Bürger, Christina, Kamchybekov, Uran, Lutgens, Esther, Figulla, Hans-Reiner, Gerdes, Norbert

Journal:

Pediatric Diabetes

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

37

Immune modulation of brown(ing) adipose tissue in obesity

van den Berg, Susan M., van Dam, Andrea D., Rensen, Patrick C.N., de Winther, Menno P.J., Lutgens, Esther

Journal:

Endocrine Reviews

Year:

2016

Language:

english

File:

PDF, 1.71 MB

english, 2016

38

CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis

Barthels, Christian, Ogrinc, Ana, Steyer, Verena, Meier, Stefanie, Simon, Ferdinand, Wimmer, Maria, Blutke, Andreas, Straub, Tobias, Zimber-Strobl, Ursula, Lutgens, Esther, Marconi, Peggy, Ohnmacht, C

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

39

Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells

Neele, Annette E, Prange, Koen HM, Hoeksema, Marten A, van der Velden, Saskia, Lucas, Tina, Dimmeler, Stefanie, Lutgens, Esther, Van den Bossche, Jan, de Winther, Menno PJ

Journal:

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

40

Erratum: CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis

Barthels, Christian, Ogrinc, Ana, Steyer, Verena, Meier, Stefanie, Simon, Ferdinand, Wimmer, Maria, Blutke, Andreas, Straub, Tobias, Zimber-Strobl, Ursula, Lutgens, Esther, Marconi, Peggy, Ohnmacht, C

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 293 KB

english, 2017

41

Atherosclerosis

Ferrari, Elena, Lutgens, Esther, Weber, Christian, Gerdes, Norbert

Journal:

Current Opinion in Lipidology

Year:

2017

Language:

english

File:

PDF, 135 KB

english, 2017

42

CD40 deficiency in smooth muscle cells ameliorates atherogenesis and promotes a stable plaque phenotype in the aortic root

Willecke, Florian, Gissler, Mark Colin, Anto Michel, Nathaly, Pfeiffer, Katharina, Härtner, Carmen, Hilgendorf, Ingo, Wolf, Dennis, Stachon, Peter, Lutgens, Esther, Holdt, Lesca M., Bode, Christoph, G

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 77 KB

english, 2017

43

CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice

Steven, Sebastian, Dib, Mobin, Hausding, Michael, Kashani, Fatemeh, Oelze, Matthias, Kröller-Schön, Swenja, Hanf, Alina, Daub, Steffen, Roohani, Siyer, Gramlich, Yves, Lutgens, Esther, Schulz, Eberhar

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 977 KB

english, 2017

44

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases

Hoogeveen, Renate M, Nahrendorf, Matthias, Riksen, Niels P, Netea, Mihai G, de Winther, Menno P J, Lutgens, Esther, Nordestgaard, Boerge, Neidhart, Michel, Stroes, Erik S G, Catapano, Alberico L, Bekk

Journal:

European Heart Journal

Year:

2017

Language:

english

File:

PDF, 463 KB

english, 2017

45

Exploring immune checkpoints as potential therapeutic targets in atherosclerosis

Kusters, Pascal, Lutgens, Esther, Seijkens, Tom T P

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

46

The SNP (rs2230500) in PRKCH Decreases the Risk of Carotid Intima-Media Thickness in a Chinese Young Adult Population

Wu, Lijun, Xi, Bo, Hou, Dongqing, Zhao, Xiaoyuan, Liu, Junting, Cheng, Hong, Zhou, Xin, Shen, Yue, Wang, Xingyu, Mi, Jie, Lutgens, Esther

Journal:

Year:

2012

Language:

english

File:

PDF, 93 KB

english, 2012

47

Histological Analysis of Extracranial Carotid Artery Aneurysms

Welleweerd, Janna C., Nelissen, Bastiaan G. L., Koole, Dave, de Vries, Jean-Paul P. M., Moll, Frans L., Pasterkamp, Gerard, Vink, Aryan, de Borst, Gert Jan, Lutgens, Esther

Journal:

Year:

2015

Language:

english

File:

PDF, 5.61 MB

english, 2015

48

Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques

Hakimzadeh, Nazanin, Pinas, Victorine A., Molenaar, Ger, de Waard, Vivian, Lutgens, Esther, van Eck-Smit, Berthe L. F., de Bruin, Kora, Piek, Jan J., Eersels, Jos L. H., Booij, Jan, Verberne, Hein J.,

Journal:

Year:

2017

Language:

english

File:

PDF, 4.49 MB

english, 2017

49

Commonly available hematological biomarkers are associated with the extent of coronary calcifications

den Harder, Annemarie M., de Jong, Pim A., de Groot, Mark C.H., Wolterink, Jelmer M., Budde, Ricardo P.J., Iŝgum, Ivana, van Solinge, Wouter W., ten Berg, Maarten J., Lutgens, Esther, Veldhuis, Wouter

Journal:

Atherosclerosis

Year:

2018

Language:

english

File:

PDF, 878 KB

english, 2018

50

Leukocyte ABCA1 Remains Atheroprotective in Splenectomized LDL Receptor Knockout Mice

Lammers, Bart, Zhao, Ying, Foks, Amanda C., Hildebrand, Reeni B., Kuiper, Johan, Van Berkel, Theo J. C., Van Eck, Miranda, Esther, Lutgens

Journal:

Year:

2012

Language:

english

File:

PDF, 461 KB

english, 2012